A Nod to disease vectors: mitigation of pathogen sensing by arthropod saliva

A Nod to disease vectors: mitigation of pathogen sensing by arthropod saliva

Arthropod saliva possesses anti-hemostatic, anesthetic, and anti-inflammatory properties that facilitate feeding and, inadvertently, dissemination of pathogens. Vector-borne diseases caused by these pathogens affect millions of people each year. Many studies address the impact of arthropod salivary proteins on various immunological components. However, whether and how arthropod saliva counters ...

Containment of arthropod disease vectors.

Effective containment of arthropod vectors of infectious diseases is necessary to prevent transmission of pathogens by released, infected vectors and to prevent vectors that escape from establishing populations that subsequently contribute to increased disease. Although rare, past releases illustrate what can go wrong and justify the need for guidelines that minimize risks. An overview of recom...

Arthropod Infestations and Vectors of Disease

Arthropod Vectors and Disease Transmission: Translational Aspects

Numerous diseases are transmitted by arthropod vectors, and for many of those diseases, effective vaccines are still not available. The contribution of the vector to the process of pathogen transmission is often overlooked, despite providing new avenues for combating vector-borne diseases, some of which could complement and significantly enhance ongoing efforts. To explore novel approaches to f...

Decoding the Ubiquitin-Mediated Pathway of Arthropod Disease Vectors

Protein regulation by ubiquitin has been extensively described in model organisms. However, characterization of the ubiquitin machinery in disease vectors remains mostly unknown. This fundamental gap in knowledge presents a concern because new therapeutics are needed to control vector-borne diseases, and targeting the ubiquitin machinery as a means for disease intervention has been already adop...